Dr. Grande is widely recognized as a world leader in cartilage repair. He pioneered the first cell-based therapy for articular cartilage repair. These studies led to the commercialization of cartilage transplantation for the current surgical treatment of focal cartilage defects in clinical use today—autologous chondrocyte transplantation.
Dr. Grande is the assistant vice president for Research Services as well as the director of Orthopaedic Research at the Feinstein Institutes for Medical Research. He also is a full-time professor at the Feinstein Institutes and a professor at the Elmezzi Graduate School of Molecular Medicine and the Zucker School of Medicine.
Dr. Grande graduated from Long Island University with a BS in biology and completed his Ph.D. in anatomy and cell biology at New York University. He completed his post-doctorate in biomechanics at the Hospital for Special Surgery. He began his scientific career at the Hospital for Joint Diseases/Orthopedic Institute studying regenerative medicine and tissue engineering technologies for repair of the musculoskeletal system. In 1990, Dr. Grande established the orthopedic research laboratory at the Feinstein Institutes for Medical Research and continues investigating novel regenerative therapies including stem cells, growth factors, biomaterials and 3D bioprinting.
He is the author of 123 peer-review publications and seven book chapters. He has been awarded nine patents and helped found two companies in the orthopedic surgery field of use. Dr. Grande serves on many committees within the United States and internationally. He regularly serves on committees doing grant reviews and regularly serves on NIH study sections for R01, R21 and SBIR/STTR grants. He is on the editorial board of the journals Cartilage and Osteoarthritis and Cartilage.